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TECHNOLOGY

Overview

Green Lipids develops ionizable lipids derived from cashew nutshell liquid for use in lipid nanoparticles that enable intracellular delivery of mRNA and other nucleic acids.

Our platform integrates:

  • Renewable feedstock chemistry
  • Rational lipid design
  • Scalable synthesis

From raw material to final formulation, the approach is designed for efficiency, affordability, adaptability and manufacture.

Process Outline

Applications

  • mRNA vaccines
  • RNA therapeutics
  • Nucleic acid transfection
  • Gene silencing and editing

Key Advantages

Sustainable Chemistry

  • Bio-based starting materials
  • Reduced environmental footprint
  • Alignment with environment, social, governance (ESG) and green chemistry principles

Cost and Supply Efficiency

  • Lower raw material input costs
  • Opportunity for regional production
  • Reduced reliance on imported speciality ionizable lipids

Design Flexibility

  • Drop-in Compatibility: our ionizable lipids are designed for seamless substitution into established LNP formulations
  • Flexible synthesis procedures:these potentially enable formation of tunable lipid structures and optimisation for different payloads and delivery targets
  • Compatibility with evolving mRNA and nucleic acids platforms

Development Status

  • Lead lipid candidates, which function efficiently in vivo, have been identified
  • Ongoing optimization and validation
  • Accredited scale-up synthesis and manufacturing processes are in progress

Intellectual Property

Green Lipids is advancing a protected lipid platform. Patent filings in key global jurisdictions have been and are being made.